There are economical and ecological concerns about utilizing peat as growth substrate and consequently a substitution is needed. Wood foam is a waste material and returning it to sustainable use is one of the main ecological tasks, besides, it has a good physical property-high water holding capacity. Therefore, the objective of this work was to research if wood foam is suitable as substitute for peat in potting media. For this, a pot experiment was conducted in the greenhouse with subsequent laboratory analysis to evaluate physical, chemical and some biological properties of the substrates. Five growth substrates were used including two target substrates where wood foam was amended in different proportions, to check the suitability in comparison with commercially available substrates. Two species, Tropaeolum nanum and Lolium perenne, were grown on the substrates and their performance evaluated. The growth experiment showed that wood foam is not suitable to substitute peat: the biomass was the lowest, fungal growth and compaction of the substrate were observed. However, total heavy metal concentrations of substrates comply with legal thresholds of Austrian compost standards and total element concentrations in plant tissue were within the optimal ranges. In conclusion, wood foam cannot be used directly, but composting may be an alternative option to avoid waste formation.